Invention Application
WO2017127627A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF
审中-公开
治疗三叉神经痛和神经病理性病原体的化合物及其用途
- Patent Title: COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF
- Patent Title (中): 治疗三叉神经痛和神经病理性病原体的化合物及其用途
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Application No.: PCT/US2017/014256Application Date: 2017-01-20
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Publication No.: WO2017127627A1Publication Date: 2017-07-27
- Inventor: TIDWELL, Richard Ray , PATRICK, Donald Alan , BUCKNER, Frederick S. , GELB, Michael H. , GILLESPIE, John R. , SILVA, Daniel Gedder
- Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL , UNIVERSITY OF WASHINGTON
- Applicant Address: 100 Europa Drive Suite 430 Chapel Hill, North Carolina 27517 US
- Assignee: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL,UNIVERSITY OF WASHINGTON
- Current Assignee: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL,UNIVERSITY OF WASHINGTON
- Current Assignee Address: 100 Europa Drive Suite 430 Chapel Hill, North Carolina 27517 US
- Agency: MURPHY, Sherry L.
- Priority: US62/281,475 20160121
- Main IPC: C07D277/66
- IPC: C07D277/66 ; C07D235/18 ; C07D471/04 ; C07D263/57 ; A61K31/426 ; A61K31/437 ; C07D417/12 ; A61K31/427 ; A61P31/00 ; C07D513/04 ; A61K31/421
Abstract:
The present invention relates to novel compounds that cross the blood-brain barrier and are effective inhibitors of neurological pathogens such as trypanosomes. The invention further relates to the use of these compounds for treating disorders related to trypanosomes and neurological pathogens.
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