Invention Application
- Patent Title: METHODS OF MIXING IMPELLER SENSING
- Patent Title (中): 混合叶轮传感方法
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Application No.: PCT/EP2016/002003Application Date: 2016-11-28
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Publication No.: WO2017129205A1Publication Date: 2017-08-03
- Inventor: WEST, Sharon D. , OSCHWALD, Martin , CUTTING, Jonathan E. , BÖTTCHER, Lars
- Applicant: SARTORIUS STEDIM BIOTECH GMBH , SARTORIUS STEDIM NORTH AMERICA INC. , SARTORIUS STEDIM SWITZERLAND AG
- Applicant Address: August-Spindler-Str. 11 37079 Göttingen DE
- Assignee: SARTORIUS STEDIM BIOTECH GMBH,SARTORIUS STEDIM NORTH AMERICA INC.,SARTORIUS STEDIM SWITZERLAND AG
- Current Assignee: SARTORIUS STEDIM BIOTECH GMBH,SARTORIUS STEDIM NORTH AMERICA INC.,SARTORIUS STEDIM SWITZERLAND AG
- Current Assignee Address: August-Spindler-Str. 11 37079 Göttingen DE
- Agency: SCHIUMA, Daniele et al.
- Priority: US15/010,317 20160129
- Main IPC: G01N11/14
- IPC: G01N11/14 ; B01F7/18 ; C12M1/02
Abstract:
The present invention relates to a method of monitoring a flow behaviour of mixed components, comprising: rotating a mixing impeller at a first speed N 1 in a mixing vessel accommodating the components to be mixed; determining a first quantity (formula I) at the first speed N 1 , wherein N 1 is the speed at which the mixing impeller rotates and P 1 is the power required to rotate the mixing impeller at the first speed N 1 ; decreasing the speed of the mixing impeller to a speed N 2 ; determining a second quantity (formula II) at the second speed N 2 , wherein N 2 is the speed at which the mixing impeller rotates and P 2 is the power required to rotate the mixing impeller at the second speed N 2 ; comparing the first quantity (formula I) and the second quantity (formula II) and detecting whether the difference between the first and second quantities is within a specified range to determine whether the flow of the components in the mixing vessel is a turbulent flow; determining the density ρ of the mixed components based on at least one speed N i for which the flow is determined to be turbulent by the formula (III) wherein ρ is the density, P i is the power required to turn the mixing impeller at the speed N i , N P,constant is the Power number for a used mixing system configuration, N i is the speed at which the mixing impeller rotates and D is the diameter of the mixing impeller; further decreasing the speed of the mixing impeller; determining the Power number N P,variable for at least one detected speed N j at which the flow is determined to be non-turbulent by the formula (IV) wherein P j is the power required to rotate the mixing impeller at the speed N j , ρ is the density previously determined based on N P,constant, N j is the speed at which the mixing impeller rotates, and D is the diameter of the mixing impeller; and determining the dynamic viscosity μ of the mixed components by the formula (V) wherein ρ is the calculated density, N j is the speed at which the mixing impeller rotates, D is the diameter of the mixing impeller, P j is the power required to rotate the mixing impeller at the speed N j and x T corresponds to a specified relationship between the Reynolds number for the used mixing system configuration and the determined Power number N P,variable . Further, the present invention relates to methods for detecting settled solids at a mixing impeller.
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