发明申请
WO2017187185A1 PEPTIDES OF BROMODOMAIN TESTIS-SPECIFIC PROTEIN (BRDT)
审中-公开
BROMODOMAIN睾丸特异性蛋白(BRDT)肽
- 专利标题: PEPTIDES OF BROMODOMAIN TESTIS-SPECIFIC PROTEIN (BRDT)
- 专利标题(中): BROMODOMAIN睾丸特异性蛋白(BRDT)肽
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申请号: PCT/GB2017/051192申请日: 2017-04-28
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公开(公告)号: WO2017187185A1公开(公告)日: 2017-11-02
- 发明人: POWLESLAND, Alex , SUN, Mei
- 申请人: IMMUNOCORE LIMITED , ADAPTIMMUNE LIMITED
- 申请人地址: 101 Park Drive Milton Park Abingdon Oxfordshire OX14 4RY GB
- 专利权人: IMMUNOCORE LIMITED,ADAPTIMMUNE LIMITED
- 当前专利权人: IMMUNOCORE LIMITED,ADAPTIMMUNE LIMITED
- 当前专利权人地址: 101 Park Drive Milton Park Abingdon Oxfordshire OX14 4RY GB
- 代理机构: KILBURN & STRODE LLP et al.
- 优先权: GB1607535.0 20160429
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; C07K7/06
摘要:
The present invention relates to novel peptides derived from Bromodomain testis-specific protein (BRDT), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.