- 专利标题: HIGH SPECIFIC ACTIVITY PREPARATION OF F-18 TETRAFLUOROBORATE
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申请号: PCT/US2017/029089申请日: 2017-04-24
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公开(公告)号: WO2017189415A8公开(公告)日: 2017-11-02
- 发明人: DEGRADO, Timothy, R. , JIANG, Huailei
- 申请人: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- 申请人地址: 200 First Street SE Rochester, MN 55905 US
- 专利权人: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- 当前专利权人: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- 当前专利权人地址: 200 First Street SE Rochester, MN 55905 US
- 代理机构: ROCHE, Richard, T.
- 优先权: US62/327,134 20160425
- 主分类号: B01J41/14
- IPC分类号: B01J41/14 ; B01J49/40 ; B01J49/57
摘要:
Embodiments of the invention provide methods of synthesizing 18 F-tetrafluoroborate ( 18 F-TFB) via direct radiofluorination on boron trifluoride (BF 3 ) to enhance both labeling yield and specific activity, Uses of 18 F-TFB are also contemplated.
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