The inventive subject matter provides a wearable device for application of methods for balancing and maintaining the health of the human autonomic nervous system, including a wearable frame; cranio-electrical stimulation (CES) circuitry and electrodes positioned on the wearable frame; and optionally including audio entrainment with binaural beats circuitry and audio outputs, and an attachable visual mask containing light-blocking material and frequency-following response visual stimulation circuitry and lights. The device may also include sensors to monitor various physiologic indicators. The system communicates the physiologic data with other devices (such as smart phones or tablets) that have algorithms to interpret the data to determine whether additional therapy is required. Based on this feedback, the smart phone communicates with the therapy elements, e.g., CES, to continue or discontinue therapy.