Systems and methods provide real time custom audio in accordance with embodiments of the invention. One method includes selecting a video stream from source multimedia content using a media server; recording a voice-over session audio recording for the video stream using the media server, where the voice-over session audio recording comprises real time custom audio for the video stream; synchronizing the timing of the voice-over session audio recording with the video stream to create a voice-over stream using the media server; and storing the voice-over stream as at least one voice-over audio stream for the source video channel using the media server.