Invention Application
WO2018076015A1 LEVERAGING THE PRESENCE OR ABSENCE OF MIRNA ISOFORMS FOR RECOMMENDING THERAPY IN CANCER PATIENTS
审中-公开
利用MIRNA异形的存在或缺乏推荐用于癌症患者的治疗
- Patent Title: LEVERAGING THE PRESENCE OR ABSENCE OF MIRNA ISOFORMS FOR RECOMMENDING THERAPY IN CANCER PATIENTS
- Patent Title (中): 利用MIRNA异形的存在或缺乏推荐用于癌症患者的治疗
-
Application No.: PCT/US2017/057909Application Date: 2017-10-23
-
Publication No.: WO2018076015A1Publication Date: 2018-04-26
- Inventor: RIGOUTSOS, Isidore , TELONIS, Aristeidis G.
- Applicant: THOMAS JEFFERSON UNIVERSITY
- Applicant Address: 901 Walnut Street Innovation Pillar Philadelphia, Pennsylvania 19107 US
- Assignee: THOMAS JEFFERSON UNIVERSITY
- Current Assignee: THOMAS JEFFERSON UNIVERSITY
- Current Assignee Address: 901 Walnut Street Innovation Pillar Philadelphia, Pennsylvania 19107 US
- Agency: VOS STRACHE, Kyle
- Priority: US62/411,417 20161021; US62/441,837 20170103; US62/502,133 20170505
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N1/30 ; G01N33/48 ; G01N33/483 ; G01N33/487 ; G01N33/50 ; G01N33/574
Abstract:
A method of identifying a subject in need of therapeutic intervention to treat a disease or condi-tion or disease recurrence or disease progression comprising, isolating isomiRs or miRNAs from a sample obtained from the subject; and characterizing the isomiRs or miRNAs and their presence or absence in the sample to identify a signature, wherein when the signature is indicative of a di-agnosis of the disease then treatment of the subject is recommended.
Information query
