Invention Application
- Patent Title: IL-1R-I BINDING POLYPEPTIDE
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Application No.: PCT/EP2018/058448Application Date: 2018-04-03
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Publication No.: WO2018178392A1Publication Date: 2018-10-04
- Inventor: FELDWISCH, Joachim , LINDBORG, Malin , NILSSON, Joakim , NORDLING, Erik , SVENSSON, Robert
- Applicant: SWEDISH ORPHAN BIOVITRUM AB (PUBL)
- Applicant Address: 112 76 Stockholm SE
- Assignee: SWEDISH ORPHAN BIOVITRUM AB (PUBL)
- Current Assignee: SWEDISH ORPHAN BIOVITRUM AB (PUBL)
- Current Assignee Address: 112 76 Stockholm SE
- Agency: AWA SWEDEN AB
- Priority: EP17164226.7 20170331
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07K14/31
Abstract:
The present disclosure relates to a class of engineered polypeptides having a binding affinity for interleukin-1 receptor type-I (IL-1R-I) which comprise the binding motif ( BM ) EX 2 X 3 X 4 X 5 X 6 X 7 EIX 10 X 11 LPNLX 16 RX 18 QYX 21 AFIX 25 X 26 LX 28 D. The present disclosure also relates to the use of such an IL-1R-I binding polypeptide as a therapeutic, prognostic and/or diagnostic agent.
Information query
