- 专利标题： PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT
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申请号： PCT/KR2018/005478申请日： 2018-05-14
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公开(公告)号： WO2018208132A1公开(公告)日： 2018-11-15
- 发明人: KIM, Pilho , CHO, Sung Yun , HA, Jae Du , KIM, Hyoung Rae , HWANG, Jong Yeon , YUN, Chang Soo , JUNG, Hee Jung , PARK, Chi Hoon , LEE, Chong Ock , LEE, Chang Hoon , AHN, Sunjoo
- 申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- 申请人地址： 141, Gajeong-ro Yuseong-gu Daejeon 34114 KR
- 专利权人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- 当前专利权人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
- 当前专利权人地址： 141, Gajeong-ro Yuseong-gu Daejeon 34114 KR
- 代理机构： LEE, Won Hee
- 优先权： KR10-2017-0059165 20170512; KR10-2018-0051686 20180504
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519 ; A23L33/10
摘要：
The present invention relates to a pyrazolopyrimidine derivative, a preparation method thereof and a pharmaceutical composition comprising the same as an active ingredient for the prevention or treatment of cancer, autoimmune disease and brain disease. The pyrazolopyrimidine derivative of the present invention exhibits excellent Bruton's tyrosine kinase inhibition activity, so that it can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer, autoimmune disease and Parkinson's disease.
