A method and apparatus for self-picking up goods, a system, an electronic device, and a storage medium, relating to the technical field of data processing. The method comprises: obtaining an acoustic wave signal generated by modulating verification information; and sending the acoustic wave signal to a self-pickup device to cause the self-pickup device to determine, according to the acoustic wave signal, whether to open a storage bin which stores goods to be picked up. A goods pickup process of a self-pickup device based on acoustic wave verification is realized.