- 专利标题： ANTI-CAR COMPOSITIONS AND METHODS
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申请号： PCT/US2018/058514申请日： 2018-10-31
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公开(公告)号： WO2019089798A1公开(公告)日： 2019-05-09
- 发明人: GILL, Saar , RUELLA, Marco
- 申请人： NOVARTIS AG , THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： NOVARTIS AG,THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- 当前专利权人： NOVARTIS AG,THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： LU, David et al.
- 优先权： US62/579,815 20171031
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C07K16/42 ; A61P35/02
摘要：
The invention provides compositions and methods for treating conditions or diseases associated with expression of a target chimeric antigen receptor (CAR) as described herein. The invention also relates to an anti-target CAR specific to the target CAR as described herein, vectors encoding the same, and recombinant T cells comprising the anti-target CARs of the present invention. The invention also includes methods of administering a genetically modified T cell expressing an anti-target CAR as described herein.
