A surgical hub is configured to transmit generator data associated with a surgical procedure from a generator of the surgical hub to a cloud-based system. The surgical hub comprises a processor and a memory storing instructions executable by the processor to: receive generator data; encrypt the generator data; generate a message authentication code based on the generator data; generate a datagram comprising: the encrypted generator data, the generated message authentication code, a source identifier and a destination identifier; and transmit the datagram to the cloud-based system. The datagram allows for the cloud-based system to: decrypt the encrypted generator data; verify the integrity of the generator data based on the message authentication code; authenticate the surgical hub as the source of the datagram; and validate a transmission path followed by the datagram between the surgical hub and the cloud based system.