- 专利标题: SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
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申请号: PCT/US2019/016127申请日: 2019-01-31
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公开(公告)号: WO2019152696A1公开(公告)日: 2019-08-08
- 发明人: KHAN, M., Amin
- 申请人: APTINYX INC.
- 申请人地址: 1801 Maple Avenue Suite 4300 Evanston, IL 60201 US
- 专利权人: APTINYX INC.
- 当前专利权人: APTINYX INC.
- 当前专利权人地址: 1801 Maple Avenue Suite 4300 Evanston, IL 60201 US
- 代理机构: BRODOWSKI, Michael, H. et al.
- 优先权: US62/624,212 20180131; US62/718,075 20180813
- 主分类号: C07D487/10
- IPC分类号: C07D487/10 ; A61P25/00 ; A61P25/24 ; A61P25/04 ; A61P25/22 ; A61P25/28 ; A61P25/18 ; A61P25/02 ; A61K31/454 ; A61K31/407
摘要:
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as other disorders.