- 专利标题: COMBINATION THERAPY FOR PI3K-ASSOCIATED DISEASE OR DISORDER
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申请号: PCT/US2019/034949申请日: 2019-05-31
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公开(公告)号: WO2019232403A1公开(公告)日: 2019-12-05
- 发明人: CANTLEY, Lewis C. , HOPKINS, Benjamin , MUKHERJEE, Siddhartha , GONCALVES, Marcus
- 申请人: CORNELL UNIVERSITY , CANTLEY, Lewis C. , HOPKINS, Benjamin , MUKHERJEE, Siddhartha , GONCALVES, Marcus
- 申请人地址: 395 Pine Tree Road, Suite 310 Ithaca, New York 14850 US
- 专利权人: CORNELL UNIVERSITY,CANTLEY, Lewis C.,HOPKINS, Benjamin,MUKHERJEE, Siddhartha,GONCALVES, Marcus
- 当前专利权人: CORNELL UNIVERSITY,CANTLEY, Lewis C.,HOPKINS, Benjamin,MUKHERJEE, Siddhartha,GONCALVES, Marcus
- 当前专利权人地址: 395 Pine Tree Road, Suite 310 Ithaca, New York 14850 US
- 代理机构: PERDOK, Monique M. et al.
- 优先权: US62/679,329 20180601
- 主分类号: A23L33/20
- IPC分类号: A23L33/20 ; A61K31/155 ; A61K38/00 ; A61P3/10 ; A61P35/00 ; C07C279/00
摘要:
Described herein are compositions and methods for treating a disease or disorder associated with PI3K signaling. For example, such compositions can include use of modulators of glucose metabolism, use of at least one kinase in the insulin-receptor/PI3K/AKT/mTOR pathway, and/or use of diet that influences the subject's metabolic state.