A drill bit includes a bit body with high and low fluid pressure bodies. The low-ressure bit body includes a fixed cutting structure, and the high-pressure bit body includes at least one high-pressure fluid channel and nozzle capable of withstanding fluid pressures greater than 40 kpsi (276 MPa). A bottomhole assembly includes a drill bit with a bit body having fixed cutter and fluid jetting portions. Low and high-pressure channels in the bit body exit in the fixed cutter and fluid jetting portions. A high-pressure nozzle is coupled to the fluid jetting portion and the high-pressure fluid channel, and a plurality of fixed cutting elements are coupled to the fixed cutter portion. A pressure intensifier is coupled to the drill bit and is configured to increase a pressure of a fluid supplied to the high-pressure fluid channel in the bit body.