- 专利标题： AAV VARIANTS WITH ENHANCED TROPISM
-
申请号： PCT/US2019/044796申请日： 2019-08-02
-
公开(公告)号： WO2020028751A3公开(公告)日： 2020-02-06
- 发明人: SAH, Dinah Wen-Yee , HOU, Jinzhao , ADACHI, Kei , WANG, Wei , CHEN, Qingmin , CARROLL, Jenna , REN, Amy , REN, Xiao-Qin , DEVERMAN, Benjamin E. , GRADINARU, Viviana , HUANG, Qin
- 申请人： VOYAGER THERAPEUTICS, INC. , CALIFORNIA INSTITUTE OF TECHNOLOGY
- 申请人地址： 75 Sidney Street Cambridge, Massachusetts 02139 US
- 专利权人： VOYAGER THERAPEUTICS, INC.,CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人： VOYAGER THERAPEUTICS, INC.,CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人地址： 75 Sidney Street Cambridge, Massachusetts 02139 US
- 代理机构： WARD, Donna T. et al.
- 优先权： US62/714,118 20180803
- 主分类号： C07K14/005
- IPC分类号： C07K14/005 ; C12N15/86
摘要：
The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.
公开/授权文献
- WO2020028751A2 AAV VARIANTS WITH ENHANCED TROPISM 公开/授权日：2020-02-06
