Invention Application
- Patent Title: METHOD TO EXPRESS, PURIFY, AND BIOTINYLATE EUKARYOTIC CELL-DERIVED MAJOR HISTOCOMPATIBILITY COMPLEXES
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Application No.: PCT/US2019/056281Application Date: 2019-10-15
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Publication No.: WO2020081537A1Publication Date: 2020-04-23
- Inventor: LOWE, Devin, B. , WOOSTER, Amanda, L.
- Applicant: TEXAS TECH UNIVERSITY SYSTEM
- Applicant Address: Office of Research Commercialization P.O. Box 42007 Lubbock, TX 79409-2007 US
- Assignee: TEXAS TECH UNIVERSITY SYSTEM
- Current Assignee: TEXAS TECH UNIVERSITY SYSTEM
- Current Assignee Address: Office of Research Commercialization P.O. Box 42007 Lubbock, TX 79409-2007 US
- Agency: CHALKER, Daniel, J. et al.
- Priority: US62/746,198 20181016
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K14/74 ; C12N15/62
Abstract:
The present invention includes compositions and methods of making and using a fusion protein comprising a peptide, a first flexible linker, a β2-microglobulin domain, a second flexible linker, a soluble major histocompatibility complex (MHC) heavy chain and a peptide tag.
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