- 专利标题: MULTIVALENT LIGANDS TARGETING CELL SURFACE RECEPTORS AND FORCE MEASUREMENT PLATFORM FOR MAKING THE SAME
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申请号: PCT/US2021/015713申请日: 2021-01-29
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公开(公告)号: WO2021155151A1公开(公告)日: 2021-08-05
- 发明人: LI, Zheng
- 申请人: THE METHODIST HOSPITAL SYSTEM
- 申请人地址: 6565 Fannin Street
- 专利权人: THE METHODIST HOSPITAL SYSTEM
- 当前专利权人: THE METHODIST HOSPITAL SYSTEM
- 当前专利权人地址: 6565 Fannin Street
- 代理机构: JACKSON BECKFORD, Shirlene et al.
- 优先权: US62/967,329 2020-01-29
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D405/14 ; A61K49/00
摘要:
Methods for probing the distribution and distance of the cell surface receptors and using the same to make multivalent ligands targeting said receptors are disclosed. Methods for making the multivalent ligands and detecting or imaging cells expressing receptors using the compounds are also provided.