- 专利标题： SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY
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申请号： PCT/US2021/024425申请日： 2021-03-26
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公开(公告)号： WO2021195533A2公开(公告)日： 2021-09-30
- 发明人: KHVOROVA, Anastasia , ROUX, Loïc Maurice René Jean , YAMADA, Ken
- 申请人： UNIVERSITY OF MASSACHUSETTS
- 申请人地址： One Beacon Street, 31st Floor
- 专利权人： UNIVERSITY OF MASSACHUSETTS
- 当前专利权人： UNIVERSITY OF MASSACHUSETTS
- 当前专利权人地址： One Beacon Street, 31st Floor
- 代理机构： VELEMA, James H. et al.
- 优先权： US63/000,328 2020-03-26
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H19/06 ; C07H19/16 ; C07H19/067 ; C07H21/02 ; C12N15/111 ; C12N15/113 ; C12N2310/31 ; C12N2310/312 ; C12N2310/314 ; C12N2310/315 ; C12N2310/321 ; C12N2310/322 ; C12N2310/3515 ; C12N2320/51
摘要：
This disclosure relates to the synthesis of novel modified oligonucleotides. The synthesis of novel phosphoramidites are also provided.
