- 专利标题: OLIGONUCLEOTIDES FOR MSH3 MODULATION
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申请号: PCT/US2021/028166申请日: 2021-04-20
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公开(公告)号: WO2021216556A2公开(公告)日: 2021-10-28
- 发明人: FERGUSON, Chantal
- 申请人: UNIVERSITY OF MASSACHUSETTS , KHVOROVA, Anastasia
- 申请人地址: One Beacon Street; 10 Rocklawn Road
- 专利权人: UNIVERSITY OF MASSACHUSETTS,KHVOROVA, Anastasia
- 当前专利权人: UNIVERSITY OF MASSACHUSETTS,KHVOROVA, Anastasia
- 当前专利权人地址: One Beacon Street; 10 Rocklawn Road
- 代理机构: SPELLBERG, Michael et al.
- 优先权: US63/012,603 2020-04-20
- 主分类号: A61K31/713
- IPC分类号: A61K31/713 ; C07H21/02 ; C12N15/09 ; C12N15/11 ; C12N15/113 ; C12Q1/68 ; A61K48/005 ; A61P25/28 ; C12N15/86 ; C12N2310/14 ; C12N2310/312 ; C12N2310/315 ; C12N2310/321 ; C12N2310/322 ; C12N2310/343 ; C12N2310/346 ; C12N2310/3515 ; C12N2320/32 ; C12N2750/14143
摘要:
This disclosure relates to novel MSH3 targeting sequences. Novel MSH3 targeting oligonucleotides for the treatment of neurodegenerative diseases are also provided.