- 专利标题： RECOMBINANT PROTEINS WITH OX40 ACTIVATING PROPERTIES
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申请号： PCT/EP2021/062453申请日： 2021-05-11
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公开(公告)号： WO2021228836A1公开(公告)日： 2021-11-18
- 发明人: LEVY, Yves , ZURAWSKI, Sandra , ZURAWSKI, Gérard
- 申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITE PARIS EST CRETEIL VAL DE MARNE , BAYLOR RESEARCH INSTITUTE , ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
- 申请人地址： 101, rue de Tolbiac; 61 Avenue du Général de Gaulle; 3434 Live Oak St; 3, Avenue Victoria
- 专利权人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE),UNIVERSITE PARIS EST CRETEIL VAL DE MARNE,BAYLOR RESEARCH INSTITUTE,ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
- 当前专利权人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE),UNIVERSITE PARIS EST CRETEIL VAL DE MARNE,BAYLOR RESEARCH INSTITUTE,ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
- 当前专利权人地址： 101, rue de Tolbiac; 61 Avenue du Général de Gaulle; 3434 Live Oak St; 3, Avenue Victoria
- 代理机构： PLASSERAUD IP
- 优先权： EP20305487.9 2020-05-13
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K14/705 ; A61P35/00 ; C07K14/70575 ; C07K14/70578 ; C07K16/2878 ; C07K2317/75 ; C07K2319/00
摘要：
The disclosure relates to the field of OX40 activating proteins. More specifically, it is disclosed herein recombinant proteins with OX40 agonist antibodies or their antigen-binding fragments fused or linked to OX40 ligand. Also disclosed is the advantageous use of such OX40 activating proteins, in particular for inducing immune responses directed to delivered antigens such as viral or cancer antigens, and/or for treating cancer.
