- 专利标题： METHODS OF TREATING PROSTATE CANCER
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申请号： PCT/US2021/035863申请日： 2021-06-04
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公开(公告)号： WO2021247977A1公开(公告)日： 2021-12-09
- 发明人: DE ALVARO, Juan , PARRA-PALAU, Josep Lluis , NIKOLOVA, Zariana , DI MARTINO, Jorge , FILVAROFF, Ellen , ARONCHIK, Ida , MALATESTA, Martina
- 申请人： CELGENE QUANTICEL RESEARCH, INC.
- 申请人地址： 9393 Town Centre Drive, Suite 110
- 专利权人： CELGENE QUANTICEL RESEARCH, INC.
- 当前专利权人： CELGENE QUANTICEL RESEARCH, INC.
- 当前专利权人地址： 9393 Town Centre Drive, Suite 110
- 代理机构： SIMKIN, Michele M. et al.
- 优先权： US63/035,622 2020-06-05
- 主分类号： A61K31/4166
- IPC分类号： A61K31/4166 ; A61K31/513 ; A61K31/573 ; A61K31/58 ; A61K45/06 ; A61P35/04
摘要：
The present application relates generally to methods for treating prostate cancer with a lysine specific demethylase-1 (LSD-1) inhibitor, wherein the lysine specific demethylase-1 (LSD-1) inhibitor resensitizes the prostate cancer cells to androgen receptor pathway inhibitor (ARPI) treatment.
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