Invention Application
- Patent Title: DRUG COMPRISING PLGA NANOPARTICLES LOADED WITH CAPE TARGETED WITH ANGIOPEP-2 PEPTIDE
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Application No.: PCT/IB2020/001053Application Date: 2020-12-07
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Publication No.: WO2021255492A1Publication Date: 2021-12-23
- Inventor: DERMAN, Serap , MANSUROGLU, Banu , BOZKURT, Yagmur , ACAR, Tayfun , SAYAN POYRAZ, Fatma
- Applicant: YILDIZ TEKNIK ÜNIVERSITESI
- Applicant Address: Yildiz Teknik Üniversitesi
- Assignee: YILDIZ TEKNIK ÜNIVERSITESI
- Current Assignee: YILDIZ TEKNIK ÜNIVERSITESI
- Current Assignee Address: Yildiz Teknik Üniversitesi
- Agency: SEVINC, Erkan
- Priority: TR2020/09490 2020-06-18
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61P35/00 ; A61K9/51 ; A61K45/06 ; A61K35/644 ; A61K31/216 ; A61K9/0019 ; A61K9/0085 ; A61K9/5153
Abstract:
The present invention provides a cancer drug for use in the treatment of cancer in which caffeic acid phenethyl ester (CAPE) is encapsulated in poly [lactic-co-glycolic acid] (PLGA) to increase its solubility in aqueous media. Angiopep-2 is used as a specific ligand to increase biological activity. In an embodiment of the invention, PLGA is preferably in the form of nanoparticles, thereby ensuring better solubility.
Information query
