Painting plate made of extruded thermoplastic material for a plate-holding cylinder of a flexographic painting unit for painting a printed support, comprises at least one painting layer (10), at least one coupling adhesive layer (20) and at least one support layer (30), wherein the painting layer (10) is formed by a material with a thermoplastic polyurethane (TPU) base mixed with at least one silicone polymer, and wherein said painting layer (10) has a hardness comprised between 50 and 60 Shore A.