Disclosed in the present invention is a continuous line annealing and pickling production method for an iron-chromium-aluminum cold-rolled coil, comprising: (1) welding two adjacent iron-chromium-aluminum cold-rolled coils to obtain a steel belt; (2) degreasing the steel belt; (3) annealing the degreased steel belt; (4) cooling the annealed steel belt; and (5) pickling the cooled steel belt. In step (3), the degreased steel belt is first preheated to 600-800°C in a heating furnace and then is heated to a final heat treatment temperature of 880-960°C, the heat preservation time is 1.0-3.0 min/mm, and the tension density in the heating furnace is 0.5-0.8 Kg/mm2. Using the production method of the present invention can produce a 1Cr13Al4 cold-rolled coil having a width of 900-1300 mm, a thickness of 0.5-1.2 mm, and a coil weight of 10 tons or above, the grain size of the coil after annealing is 4-6 levels, the mechanical properties satisfy the requirements of GB/T 1234-2012 High Resistance Alloys for Electrical heating, and the finished product has a qualified 2B surface.