A display substrate (10) and a manufacturing method therefor, and a display apparatus (2). The display substrate (10) comprises a base substrate (100), and a first gate driving circuit and a plurality of signal lines (SL105) that are arranged in a peripheral region (106) of the base substrate (100); the first gate driving circuit comprises a plurality of shift register units (105); the plurality of signal lines (SL105) are configured to respectively provide a trigger signal, a clock signal, and a power supply signal to the plurality of shift register units (105); each signal line (SL105) comprises a first conductive portion (501); for at least one signal line (SL105), the display substrate (10) comprises a plurality of layers of insulating patterns (400) located at the side of the first conductive portion (501) of each signal line (SL105) distant from the base substrate (100), and at least one layer of the insulating pattern covers the surface of the side of the first conductive portion (501) distant from the base substrate (100); a first insulating pattern (401) in the plurality of layers of insulating patterns (400) comprises a recess (4011); the orthographic projection of the recess (4011) on the base substrate (100) is at least partially located in a region surrounded by the orthographic projection of the first conductive portion (501) on the base substrate (100); and the material of the first insulating pattern (401) comprises an organic insulating material. The display substrate (10) facilitates narrow bezel design.