Invention Application
- Patent Title: NANOFORMULATIONS OF PAZOPANIB, COMPOSITIONS COMPRISING THE SAME AND METHODS OF TREATING OSTEOARTHRITIS
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Application No.: PCT/US2022/032663Application Date: 2022-06-08
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Publication No.: WO2022261199A1Publication Date: 2022-12-15
- Inventor: SAMPEN, Hee-jeong, Im , LIU, Ying
- Applicant: THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Applicant Address: 810 Vermont Ave NW; 352 Henry Administration Building
- Assignee: THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee: THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee Address: 810 Vermont Ave NW; 352 Henry Administration Building
- Agency: KLIEM, Michele, A. et al.
- Priority: US63/208,137 2021-06-08
- Main IPC: A61K31/33
- IPC: A61K31/33 ; A61K31/495 ; A61K31/505 ; A61K31/00
Abstract:
Disclosed herein are nanoparticles comprising Pazopanib or a derivative thereof encapsulated by the copolymer poly(lactic-co-gly colic acid) (PLGA). Also disclosed herein are methods for treating osteoarthritis, inhibiting or preventing cartilage degeneration, and reducing or inhibiting pain-associated depression in subjects with joint pain with nanoparticles comprising Pazopanib or a derivative thereof.
Information query
