- 专利标题: HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS
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申请号: PCT/CN2022/098492申请日: 2022-06-13
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公开(公告)号: WO2022262691A1公开(公告)日: 2022-12-22
- 发明人: CHEN, Xiangyang , PANG, Yucheng
- 申请人: BEIJING INNOCARE PHARMA TECH CO., LTD.
- 申请人地址: Bldg. 8, No. 8 Life Science Park Rd., Changping District
- 专利权人: BEIJING INNOCARE PHARMA TECH CO., LTD.
- 当前专利权人: BEIJING INNOCARE PHARMA TECH CO., LTD.
- 当前专利权人地址: Bldg. 8, No. 8 Life Science Park Rd., Changping District
- 代理机构: INTELIGHT IP LAW FIRM
- 优先权: US63/211,840 2021-06-17
- 主分类号: C07D403/12
- IPC分类号: C07D403/12 ; C07D405/14 ; C07D409/04 ; C07D487/00 ; C07D487/02 ; A61K31/517 ; A61P35/00
摘要:
Provided herein are heterocyclic compounds shown in Formula (I) and their pharmaceutically acceptable salts thereof suitable for inhibiting or regulating the activity of SOS1. These compounds are useful for preventing and/or treating SOS1-mediated diseases, in particular cancers. Aslo provided are methods for preparing the mentioned compounds.