Invention Application
- Patent Title: PHARMACOGENOMICS SCORE TO MAKE DECISIONS ON THERAPY AUGMENTATION IN AML
-
Application No.: PCT/US2022/040326Application Date: 2022-08-15
-
Publication No.: WO2023022976A1Publication Date: 2023-02-23
- Inventor: LAMBA, Jatinder, Kaur , ELSAYED, Abdelrahman, H. , CAO, Xueyuan , POUNDS, Stanley
- Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED , ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. , UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Applicant Address: 223 Grinter Hall; 262 Danny Thomas Place; UT Conference Center
- Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED,ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.,UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED,ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.,UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
- Current Assignee Address: 223 Grinter Hall; 262 Danny Thomas Place; UT Conference Center
- Agency: MACDONALD, Kevin et al.
- Priority: US63/233,673 2021-08-16
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; A61P35/02
Abstract:
The disclosure relates to methods for characterizing and/or treating a subject having cancer, said methods comprising performing an assay to identify the nucleotides present at each of a set of single-nucleotide polymorphism (SNP) locations within the cytarabine (ara-C) pathway, assigning a genotype score for the identified nucleotides of each SNP, and characterizing the subject having cancer based on the summation of the assigned genotype scores. In some embodiments, treatment is administered based upon the characterization of the subject, according to the methods described herein.
Information query
IPC分类:
