A thermally controlled payload container for carrying payloads by an Unmanned Aerial Vehicle (UAV) comprising an inner wall and an outer wall. The inner wall forms a chamber having an open end and a closed end. The payload container also comprises a thermal control body adjacent to the inner wall and disposed between the inner wall and the outer wall. The payload container also comprises a thermoelectric cooler (TEC) extending through the outer wall from a first side of the TEC to a second side of the TEC, the first side adjacent the thermal control body and the second side coupled to an external heat sink.