The present invention relates to a disinfection device using ultrasonic waves, comprising: a vaporization unit in which a disinfecting fluid is stored, and which uses ultrasonic waves to generate microbubbles by means of low temperature boiling; a body part to which a plurality of spray nozzles for spraying, to the outside, the disinfecting fluid changed into microbubbles by the vaporization unit is exposed; a sensor unit, which is included in the body part and senses an approaching object; a temperature measurement unit, which is included in the body part and measures the body temperature of the approaching object; and a control unit, which receives a sensing value from the sensor unit so as to spray, through the spray nozzles, the disinfecting fluid changed into microbubbles.