发明申请
- 专利标题： ANTAGONISTS OF GPR39 PROTEIN
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申请号： PCT/US2022/047658申请日： 2022-10-25
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公开(公告)号： WO2023076219A2公开(公告)日： 2023-05-04
- 发明人: CIANCIULLI, Agostino , MICHELI, Fabrizio , TRIST, Iuni Margaret Laura
- 申请人： VASOCARDEA, INC.
- 申请人地址： 2010 SW Carter Lane
- 专利权人： VASOCARDEA, INC.
- 当前专利权人： VASOCARDEA, INC.
- 当前专利权人地址： 2010 SW Carter Lane
- 代理机构： ECHOLS, Kelly A. et al.
- 优先权： US63/272,076 2021-10-26
- 主分类号： C07D491/10
- IPC分类号： C07D491/10 ; C07D413/10 ; C07D417/10 ; C07D417/14 ; C07D413/14 ; C07D471/04 ; C07D403/14 ; C07D403/10 ; C07D401/14 ; C07D401/10 ; C07D405/14 ; A61K31/454 ; A61K31/496 ; A61K31/451 ; A61K31/5355
摘要：
Novel compounds that act as antagonists to human GPR39 protein are disclosed. Pharmaceutical compositions and methods of use for antagonists to human GPR39 protein are disclosed. In particular, methods of using the antagonists in the treatment of diseases or conditions including cardiovascular conditions, endocrine system and hormone disorders, cancer disorders, metabolic diseases, gastrointestinal and liver diseases, hematological disorders, neurological disorders and respiratory diseases are disclosed herein.
