公开(公告)号：EP3295710B1

公开(公告)日：2019-06-12

申请号：EP16724752.7

申请日：2016-04-26

申请人： Cisco Technology, Inc.

发明人： THUBERT, Pascal ,  LEVY-ABEGNOLI, Eric ,  WETTERWALD, Patrick ,  VASSEUR, Jean-Philippe

IPC分类号： H04L12/751 ,  H04W40/02 ,  H04L12/707 ,  H04L12/801 ,  H04L12/933 ,  H04W36/00 ,  H04W84/18

公开(公告)号：EP1931698B1

公开(公告)日：2019-05-29

申请号：EP06815963.1

申请日：2006-10-03

申请人： Alexion Pharmaceuticals, Inc.

发明人： HARVEY, Alex J.

IPC分类号： C07K14/16 ,  C07K19/00

公开(公告)号：EP2252952B1

公开(公告)日：2019-03-13

申请号：EP09704346.7

申请日：2009-01-23

申请人： Biogen MA Inc.

发明人： CUNNIEN, Paul ,  GANGULY, Joydeep ,  GHOSH, Basav ,  LADIWALA, Asif ,  SONG, Robert ,  THOMMES, Jorg

IPC分类号： G06F19/00 ,  G01N30/34 ,  G01N30/88 ,  G01N30/86 ,  G05B19/00

公开(公告)号：EP1929974B1

公开(公告)日：2019-03-13

申请号：EP08101273.4

申请日：1998-06-19

申请人： Align Technology, Inc.

发明人： Chishti, Muhammad ,  Lerios, Apostolos ,  Freyburger, Brian ,  Wirth, Kelsey ,  Ridgley, Richard

IPC分类号： A61C7/00

公开(公告)号：EP3427693A1

公开(公告)日：2019-01-16

申请号：EP18180495.6

申请日：2011-09-27

申请人： KeraMed, Inc.

发明人： Shiuey, Yichieh ,  Rehal, Michael

IPC分类号： A61F2/16 ,  A61F2/14 ,  A61F2/00

摘要： An artificial cornea is formed from a hydro gel polymer and includes a monolithic body having a center optic surrounded by an annular rim. Artificial cornea is inserted into a central anterior opening in a cornea so that the annular rim enters an annular pocket surrounding the opening. The height of the center optic matches the depth of the central opening so that the level of the artificial cornea matches that of the native cornea.

公开(公告)号：EP3377636A1

公开(公告)日：2018-09-26

申请号：EP16867316.8

申请日：2016-11-20

申请人： Oregon Health & Science University

发明人： NELSON, Jay ,  HANSEN, Scott ,  HANCOCK, Meaghan, H. ,  PICKER, Louis ,  FRUEH, Klaus

IPC分类号： C12N15/86 ,  A61K39/00 ,  A61K39/015 ,  A61K39/04 ,  A61K39/12 ,  A61K48/00

CPC分类号： A61K39/00 ,  A61K39/12 ,  A61K2039/5256 ,  A61K2039/552 ,  A61K2039/572 ,  C12N15/86 ,  C12N2710/16134 ,  C12N2710/16143 ,  C12N2740/15034

摘要： Disclosed herein are recombinant CMV vectors comprising heterologous antigens and microRNA recognition elements to silence expression of CMV genes in the presence of microRNA derived from myeloid cells, an active UL128 protein and an active UL130 protein. Also disclosed are recombinant CMV vectors comprising heterologous antigens and microRNA recognition elements to silence expression of CMV genes in the presence of microRNA derived from myeloid cells, an inactive UL128 protein and an inactive UL130 protein. Also disclosed are methods of generating an unconventional immune response using these vectors. Such an immune response is characterized by generation of a CD8+ T cell response that is predominantly restricted by MHC-II.

公开(公告)号：EP2561656B1

公开(公告)日：2018-08-22

申请号：EP11717857.4

申请日：2011-04-18

申请人： Cisco Technology, Inc.

发明人： CHEN, Wei ,  ZHU, Xiaopu ,  LIU, Zhiyu ,  ZHANG, Pubing

IPC分类号： H04L29/08 ,  H04L12/18 ,  H04L12/58

CPC分类号： H04L41/20 ,  H04L12/1813 ,  H04L51/04 ,  H04L67/02 ,  H04L67/142

摘要： A communication system and method include a server hosting an interactive voice response or self-help application in a Java virtual machine. In order to leverage the advantages and facilities of the Java servlet model, a Java XMPP (Extensible Messaging and Presence Protocol) servlet container is provided for the server so that the communication application can be programmed with objects defined by an XMPP servlet API, as well as objects defined by the standards-based Java EE platform such as HTTP and SIP servlets, in order to service an XMPP client. In addition to the generic class objects of the Java servlet model, the API also provides a set of XMPP-specific class objects. The Java XMPP servlet container includes a network point at a transport level for handling network connections, an XMPP service layer for managing XMPP sessions and streams, and an application layer for managing XMPP stanzas.

公开(公告)号：EP3331550A1

公开(公告)日：2018-06-13

申请号：EP16833893.7

申请日：2016-08-04

申请人： Acceleron Pharma Inc.

发明人： KUMAR, Ravindra ,  SURAGANI, Naga, Venkata Sai Rajasekhar

IPC分类号： A61K38/17 ,  C07K14/735 ,  C07K14/71 ,  C07K19/00 ,  A61P35/00 ,  A61P19/00

CPC分类号： C07K14/495 ,  A61K31/519 ,  A61K45/06 ,  C07K14/71 ,  C07K2319/30 ,  A61K2300/00

摘要： In part, the present disclosure relates methods for treating, preventing, or reducing the severity of a myeloproliferative disorder (e.g., polycythemia vera, essential thrombocythemia, and myelofibrosis) or one or more complications of a myeloproliferative disorder. The present disclosure further relates methods for treating, preventing, or reducing the severity of a Janus kinase-associated disorder or one or more complications of a Janus kinase-associated disorder. In certain aspects the disclosure provides TβRII antagonists for treating, preventing, or reducing the severity of a myeloproliferative disorder (e.g., polycythemia vera, essential thrombocythemia, and myelofibrosis) or a Janus kinase-associated disorder or one or more complications of a myeloproliferative disorder or a Janus kinase-associated disorder.

公开(公告)号：EP1535438B1

公开(公告)日：2018-04-18

申请号：EP03767126.0

申请日：2003-08-05

申请人： Cisco Technology, Inc.

发明人： KIEN, Thai-Bao, H. ,  AO, Jiening ,  WEST, Lamar, E., Jr.

IPC分类号： H04L27/14 ,  H04L27/00 ,  H04L5/14

CPC分类号： H04L27/0014 ,  H04L5/143

摘要： The present invention provides an apparatus and method for detecting the presence of a carrier signal that is included in the reverse signals of a communications system. The present invention uses an improved apparatus that determines the average power of the reverse signals during a predetermined counting cycle. The average power is then compared to a threshold power value. If the average power exceeds the threshold power value, an enable signal is provided to allow further transmission of the reverse signals.

公开(公告)号：EP1917796B1

公开(公告)日：2018-03-14

申请号：EP06813223.2

申请日：2006-07-19

申请人： Cisco Technology, Inc.

发明人： SHAFFER, Shmuel ,  PATEL, Lebhesh ,  CHRISTENSON, Steven, L.

IPC分类号： H04M3/56 ,  H04M3/42

CPC分类号： H04M3/42348 ,  H04M3/487 ,  H04M3/56 ,  H04M2203/5054 ,  H04M2242/15

摘要： A method for managing conference resources includes receiving from an endpoint of a user a call to join a multipoint conference between a plurality of participants. Each participant communicates on the multipoint conference through a respective endpoint. The method includes determining that an insufficient amount of resources exist to allow the user to communicate on the multipoint conference and determining participation instructions to enable the user to communicate on the multipoint conference. The method also includes communicating the participation instructions. Location information associated with the user and location information associated with at least one of the plurality of participants may be used to determine the participation instructions to enable the user to communicate on the multipoint conference.