APPARATUS AND METHODS FOR DELIVERING HEMOSTATIC MATERIALS FOR BLOOD VESSEL CLOSURE
    4.
    发明公开
    APPARATUS AND METHODS FOR DELIVERING HEMOSTATIC MATERIALS FOR BLOOD VESSEL CLOSURE 有权
    DEVICE FOR RELEASE血液母乳喂养材料的用于血管的关闭

    公开(公告)号:EP2293724A1

    公开(公告)日:2011-03-16

    申请号:EP09774368.6

    申请日:2009-06-30

    IPC分类号: A61B17/08

    摘要: Apparatus for sealing a vascular wall penetration disposed at the end of the tissue tract comprises a shaft, an occlusion element, a hemostatic implant, and a protective sleeve. The apparatus is deployed through the tissue tract with the occlusion element temporarily occluding the vascular wall penetration and inhibiting backbleeding therethrough. The hemostatic implant, which will typically be a biodegradable polymer such as collagen carrying an anti-proliferative agent or coagulation promoter, will then be deployed from the sealing apparatus and left in place to enhance closure of the vascular wall penetration with minimum scarring. The implant may be radiopaque to allow observation before release.

    摘要翻译: 装置用于密封在所述组织管道的端部设置的血管壁渗透包括轴到闭塞元件,止血植入体,和一个保护套。 该装置通过与闭塞元件暂时堵塞血管壁穿透和抑制通过backbleeding那里组织管道展开。 止血植入体的,而这些通常是生物可降解的聚合物:例如胶原承载上抗增殖剂或凝​​血启动子,然后将从密封装置部署和留在原地,以加强与最小的疤痕血管壁渗透的闭合。 植入物可以是不透射线的允许观察发布之前。

    SELF-TENSIONING VASCULAR OCCLUSION DEVICE AND METHOD FOR ITS USE
    5.
    发明公开
    SELF-TENSIONING VASCULAR OCCLUSION DEVICE AND METHOD FOR ITS USE 有权
    具有自电压血管闭合装置

    公开(公告)号:EP1748733A2

    公开(公告)日:2007-02-07

    申请号:EP05759503.5

    申请日:2005-05-18

    IPC分类号: A61B17/03

    摘要: The present invention advantageously provides self-tensioning occlusion devices, systems, and methods for percutaneous access and closure of vascular puncture sites. One device comprises a catheter body, an occlusion member, and a tensioning member. The occlusion member, such an expansible member, is disposed on a distal end of the body. The tensioning member, such as a spring or coil, is slidably disposed over the body and proximal the expansion member. Generally, during application, the tensioning member will be deployed against subcutaneous tissue so as to apply tension to the expansible member against the puncture site. The substantial hold once the tension is applied is then provided by external means, such as an anchoring clip.

    VASCULAR CLOSURE DEVICES FOR PROVIDING HEMOSTATIC ENHANCEMENT
    6.
    发明授权
    VASCULAR CLOSURE DEVICES FOR PROVIDING HEMOSTATIC ENHANCEMENT 有权
    用于提供静脉内增强的血管闭合装置

    公开(公告)号:EP2162071B1

    公开(公告)日:2017-05-03

    申请号:EP08772314.4

    申请日:2008-07-01

    IPC分类号: A61B17/03

    摘要: Drug eluting vascular closure devices and methods for closing a blood vessel puncture site disposed at a distal end of a tissue tract are described. The devices and methods rely on a combination of the body's own natural mechanism to achieve hemostasis with chemical and/or biological agents to accelerate the hemostatic process. One method includes the steps of introducing a closure device through the tissue tract and deploying an expansible member at a distal end of the device within the blood vessel to occlude the puncture site. A chemical and/or biological sealing member disposed proximal the expansible member is then displaced so as to expose a chemical and/or biological region or release region of the device. At least one chemical and/or biological agent is thereafter released from the device and into the tissue tract to accelerate the occlusion process in the tract.

    摘要翻译: 描述了药物洗脱血管闭合装置和关闭布置在组织管道远端的血管穿刺部位的方法。 该装置和方法依靠人体自身机制的组合来实现止血与化学和/或生物制剂以加速止血过程。 一种方法包括通过组织管道引入闭合装置并在血管内的装置的远端部署可膨胀构件以闭塞穿刺部位的步骤。 然后置于可膨胀构件附近的化学和/或生物密封构件移位,以暴露装置的化学和/或生物学区域或释放区域。 此后,至少一种化学和/或生物制剂从装置释放并进入组织道以加速道内的阻塞过程。

    VASCULAR CLOSURE DEVICES AND METHODS PROVIDING HEMOSTATIC ENHANCEMENT
    7.
    发明公开
    VASCULAR CLOSURE DEVICES AND METHODS PROVIDING HEMOSTATIC ENHANCEMENT 有权
    GEFÄSSVERSCHLUSSVORRICHTUNGENFÜRVERSTÄRKTEHÄMOSTATISCHEWIRKUNG

    公开(公告)号:EP2162071A1

    公开(公告)日:2010-03-17

    申请号:EP08772314.4

    申请日:2008-07-01

    IPC分类号: A61B17/03

    摘要: Drug eluting vascular closure devices and methods for closing a blood vessel puncture site disposed at a distal end of a tissue tract are described. The devices and methods rely on a combination of the body's own natural mechanism to achieve hemostasis with chemical and/or biological agents to accelerate the hemostatic process. One method includes the steps of introducing a closure device through the tissue tract and deploying an expansible member at a distal end of the device within the blood vessel to occlude the puncture site. A chemical and/or biological sealing member disposed proximal the expansible member is then displaced so as to expose a chemical and/or biological region or release region of the device. At least one chemical and/or biological agent is thereafter released from the device and into the tissue tract to accelerate the occlusion process in the tract.

    摘要翻译: 描述药物洗脱血管闭合装置和用于闭合设置在组织管的远端处的血管穿刺部位的方法。 装置和方法依赖于身体自身机制的组合,以通过化学和/或生物剂来止血以加速止血过程。 一种方法包括以下步骤:通过组织道引入闭合装置,并在血管内的装置的远端部署可膨胀构件以阻塞穿刺部位。 设置在可膨胀构件附近的化学和/或生物密封构件然后被移位,以暴露设备的化学和/或生物区域或释放区域。 此后,至少一种化学和/或生物剂从该装置中释放并进入组织道,以加速该道中的闭塞过程。

    DEVICE AND METHOD FOR SEALING BLOOD VESSELS
    8.
    发明公开
    DEVICE AND METHOD FOR SEALING BLOOD VESSELS 审中-公开
    用于密封血管的装置和方法

    公开(公告)号:EP1732450A2

    公开(公告)日:2006-12-20

    申请号:EP05735344.3

    申请日:2005-04-06

    发明人: YASSINZADEH, Zia

    IPC分类号: A61B17/08

    摘要: The present invention provides devices, systems, and methods for percutaneously sealing a puncture site in tissue tracts and vessels in human or animal bodies. One system includes a locating assembly that is used to locate the puncture site and can also provide temporary hemostasis when the system is used for closing a vessel puncture. The system also includes a compression assembly comprising a tubular member with a balloon on a distal end thereof. This balloon is at a fixed distance from the locator tip which locates the balloon outside the vessel wall at a predetermined distance. Inflation of this balloon causes forward elongation of the balloon which compresses subcutaneous tissue between the distal tip of the balloon and the vessel wall. This tissue compression against the puncture site is the mechanism that provides hemostasis.

    摘要翻译: 本发明提供了用于经皮密封人或动物体内组织束和血管中的穿刺部位的装置,系统和方法。 一个系统包括定位组件,该定位组件用于定位穿刺部位,并且还可以在系统用于关闭血管穿刺时提供临时止血。 该系统还包括压缩组件,该压缩组件包括在其远端上具有球囊的管状构件。 该气囊与定位器尖端相距固定的距离,该定位器尖端将气囊定位在血管壁外预定距离处。 该气囊的膨胀引起气囊向前伸长,气囊压缩气囊远端尖端和血管壁之间的皮下组织。 针对穿刺部位的这种组织压缩是提供止血的机制。

    VASCULAR CLOSURE DEVICES AND METHODS PROVIDING HEMOSTATIC ENHANCEMENT
    10.
    发明公开
    VASCULAR CLOSURE DEVICES AND METHODS PROVIDING HEMOSTATIC ENHANCEMENT 有权
    GEFÄSSVERSCHLUSSVORRICHTUNGENUND VERFAHRENFÜRVERSTÄRKTEHÄMOSTATISCHEWIRKUNG

    公开(公告)号:EP2162071A4

    公开(公告)日:2013-08-07

    申请号:EP08772314

    申请日:2008-07-01

    IPC分类号: A61B17/03

    摘要: Drug eluting vascular closure devices and methods for closing a blood vessel puncture site disposed at a distal end of a tissue tract are described. The devices and methods rely on a combination of the body's own natural mechanism to achieve hemostasis with chemical and/or biological agents to accelerate the hemostatic process. One method includes the steps of introducing a closure device through the tissue tract and deploying an expansible member at a distal end of the device within the blood vessel to occlude the puncture site. A chemical and/or biological sealing member disposed proximal the expansible member is then displaced so as to expose a chemical and/or biological region or release region of the device. At least one chemical and/or biological agent is thereafter released from the device and into the tissue tract to accelerate the occlusion process in the tract.

    摘要翻译: 描述药物洗脱血管闭合装置和用于闭合设置在组织管的远端处的血管穿刺部位的方法。 装置和方法依赖于身体自身机制的组合,以通过化学和/或生物剂来止血以加速止血过程。 一种方法包括以下步骤:通过组织道引入闭合装置,并在血管内的装置的远端部署可膨胀构件以阻塞穿刺部位。 设置在可膨胀构件附近的化学和/或生物密封构件然后被移位,以暴露设备的化学和/或生物区域或释放区域。 此后,至少一种化学和/或生物剂从该装置中释放并进入组织道,以加速该道中的闭塞过程。