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公开(公告)号:EP4190325A1
公开(公告)日:2023-06-07
申请号:EP21854525.9
申请日:2021-08-02
发明人: KOBAYAKAWA, Ko , KOBAYAKAWA, Reiko
IPC分类号: A61K31/26 , A61K31/426 , A61K31/44 , A61K31/4965 , A61K31/54 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24
摘要: The present invention provides a medicament that exerts a psychotropic action through selective sensory nerve stimulation. A prophylactic or therapeutic agent for a psychiatric disorder, containing, as an active ingredient, at least one kind selected from a heterocyclic compound represented by the formula (I)
wherein each symbol is as described in the specification, or a salt thereof, and an isothiocyanate compound represented by the formula S=C=N-R 5 (II) wherein each symbol is as described in the specification.-
公开(公告)号:EP4129065A1
公开(公告)日:2023-02-08
申请号:EP21775596.6
申请日:2021-03-25
发明人: KOBAYAKAWA, Ko , KOBAYAKAWA, Reiko
摘要: A repellent for mammals containing a repellent active ingredient effective for mammals is provided. A repellent for mammals containing, as an active ingredient, at least one selected from a thiophene compound represented by the formula (Ia) :
wherein R 1A , R 2A , R 3A , and R 4A are each independently a hydrogen atom, an acyl group, an optionally esterified carboxyl group, a halogen atom, an optionally substituted alkyl group, an optionally substituted alkoxy group, an optionally substituted thiol group, or an optionally substituted amino group;
R 3A and R 4A are optionally bonded to each other to form a benzene ring together with carbon atoms bonded thereto; provided that R 1A , R 2A , R 3A , and R 4A are not hydrogen atoms at the same time,
and a salt thereof.-
公开(公告)号:EP3766492A1
公开(公告)日:2021-01-20
申请号:EP19766641.5
申请日:2019-03-15
发明人: KOBAYAKAWA, Ko , KOBAYAKAWA, Reiko
IPC分类号: A61K31/425 , A01N1/02 , A61K31/167 , A61K31/26 , A61K31/341 , A61K31/352 , A61K31/381 , A61K31/40 , A61K31/426 , A61K31/428 , A61K31/44 , A61K31/4406 , A61K31/4965 , A61K31/522 , A61K31/5375 , A61K31/54 , A61K31/5415 , A61K31/55 , A61K45/00 , A61P9/10 , A61P25/00
摘要: The present invention provides a prophylactic or therapeutic agent for hypoxic injury, ischemia-reperfusion injury or inflammation, an agent for protecting cells for transplantation, and an agent for preserving organism. A prophylactic or therapeutic agent for hypoxic injury, ischemia-reperfusion injury or inflammation, an agent for protecting cells for transplantation, or an agent for preserving organism, containing, as an active ingredient, at least one kind selected from a heterocyclic compound represented by the formula (I)
wherein each symbol is as described in the DESCRIPTION, or a salt thereof; an isothiocyanate compound represented by the formula S=C=N-R 5 (II) wherein the symbol is as described in the DESCRIPTION; and a TRPA1 agonist.-
公开(公告)号:EP2534949A1
公开(公告)日:2012-12-19
申请号:EP11739922.0
申请日:2011-02-08
发明人: KOBAYAKAWA, Ko , KOBAYAKAWA, Reiko
IPC分类号: A01N31/02 , A01N43/02 , A01N43/10 , A01N43/36 , A01N43/78 , A01N43/84 , A01N47/46 , A01P17/00
摘要: The present invention provides an animal repellent comprising, as an active ingredient, a compound having an odor innately inducing fear in animals, which is free from acclimation of animals to the aforementioned odor. The present invention relates to animal repellent comprising, as an active ingredient, at least one kind selected from a heterocyclic compound represented by the formula (1) :
wherein ring A is a 3- to 7-membered heterocycle containing at least one hetero atom selected from a nitrogen atom, a sulfur atom and an oxygen atom, and R 1 and R 2 are each independently hydrogen, a halogen atom, an optionally substituted alkyl group, an optionally substituted alkoxy group, an acyl group, an optionally esterified carboxyl group, an optionally substituted thiol group, an optionally substituted amino group or an oxo group, or a salt thereof, a chain sulfide compound and alkyl isothiocyanate.摘要翻译: 本发明提供一种动物驱避剂,其包含作为活性成分的具有气味的化合物,其在动物中引起恐惧,其不具有适应动物至上述气味的作用。 本发明涉及动物驱避剂,其包含作为活性成分的选自由式(1)表示的杂环化合物中的至少一种:其中环A为含有至少一个选择的杂原子的3-至7-元杂环 从氮原子,硫原子和氧原子,R 1和R 2各自独立地为氢,卤素原子,任选取代的烷基,任选取代的烷氧基,酰基,任意酯化的羧基, 任选取代的硫醇基,任选取代的氨基或氧代基,或其盐,链硫化合物和异硫氰酸烷基酯。
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