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1.发明公开ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF 审中-公开“与硫酸化组含表位，抗体此类表位和孤立分子及其用途”
公开(公告)号：EP1406930A2
公开(公告)日：2004-04-14
申请号：EP01994330.7
申请日：2001-12-31
发明人： LAZAROVITS, Janette , HAGAI, Yocheved , PLAKSIN, Daniel , VOGEL, Tikva , NIMROD, Abraham , MAR-HAIM, Hagit , SZANTHON, Ester , RICHTER, Tamar , AMIT, Boaz , KOOPERMAN, Lena , PERETZ, Tuvia , LEVANON, Avigdor
IPC分类号： C07K16/00
CPC分类号： C07K16/3061 , A61K38/00 , C07K14/472 , C07K2317/565 , C07K2317/622
摘要： The present invention provides epitopes present on cancer cells and important in physiological phenomena such as cell rolling, metastasis, and inflammation. Therapeutic and diagnostic methods and compositions using antibodies capable of binding to the epitopes are provided. Methods and compositions according to the present invention can be used in diagnosis of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease.
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