公开(公告)号：EP0711771A3

公开(公告)日：1996-07-10

申请号：EP95120531.9

申请日：1990-02-08

申请人： BIOCHEM PHARMA INC.

发明人： Belleau, Bernard ,  Nguyen-Ba, Nghe ,  Belleau, Pierette

IPC分类号： C07D473/00 ,  C07D411/04

CPC分类号： C07D411/14 ,  C07D327/04 ,  C07D405/04 ,  C07D411/04 ,  C07D473/00 ,  C07D473/40

摘要： Disclosed are compounds of the formula

wherein R₁ is hydrogen;
   R₂ is a purine or pyrimidine base or an analogue or derivative thereof;
   Z is S, S=O or SO₂; and
   pharmaceutically acceptable derivatives thereof. Also described are use of the compounds as antiviral agents, pharmaceutical formulations, and methods for the preparation of the compounds.

公开(公告)号：EP0382526A2

公开(公告)日：1990-08-16

申请号：EP90301335.7

申请日：1990-02-08

申请人： BIOCHEM PHARMA INC.

发明人： Belleau, Bernard (deceased) ,  Belleau, Pierette ,  Nguyen-Ba, Nghe

IPC分类号： C07D473/00 ,  C07D411/04 ,  C07D411/14 ,  C07D327/04 ,  A61K31/52 ,  A61K31/505

CPC分类号： C07D411/14 ,  C07D327/04 ,  C07D405/04 ,  C07D411/04 ,  C07D473/00 ,  C07D473/40

摘要： Disclosed are compounds of the formula
wherein R₁ is hydrogen;
R₂ is a purine or pyrimidine base or an analogue or derivative thereof;
Z is S, S=O or SO₂; and
pharmaceutically acceptable derivatives thereof.
Also described are use of the compounds as antiviral agents, pharmaceutical formulations, and methods for the preparation of the compounds.

摘要翻译： 公开了式CHEM的化合物，其中R 1是氢; R2是嘌呤或嘧啶碱基或其类似物或衍生物; Z是S，S = O或SO 2; 及其药学上可接受的衍生物。 还描述了化合物作为抗病毒剂，药物制剂和制备化合物的方法的用途。

公开(公告)号：EP0711771A2

公开(公告)日：1996-05-15

申请号：EP95120531.9

申请日：1990-02-08

申请人： BIOCHEM PHARMA INC.

发明人： Belleau, Bernard ,  Nguyen-Ba, Nghe ,  Belleau, Pierette

IPC分类号： C07D473/00 ,  C07D411/04

CPC分类号： C07D411/14 ,  C07D327/04 ,  C07D405/04 ,  C07D411/04 ,  C07D473/00 ,  C07D473/40

摘要： Disclosed are compounds of the formula

wherein R₁ is hydrogen;
   R₂ is a purine or pyrimidine base or an analogue or derivative thereof;
   Z is S, S=O or SO₂; and
   pharmaceutically acceptable derivatives thereof.
Also described are use of the compounds as antiviral agents, pharmaceutical formulations, and methods for the preparation of the compounds.

摘要翻译： 公开了下式的化合物：其中R 1是氢; R 2是嘌呤或嘧啶碱或其类似物或衍生物; Z是S，S = O或SO 2; 及其药学可接受的衍生物。 还描述了这些化合物作为抗病毒剂，药物制剂和制备该化合物的方法的用途。

公开(公告)号：EP0382526B1

公开(公告)日：1996-05-15

申请号：EP90301335.7

申请日：1990-02-08

申请人： BIOCHEM PHARMA INC.

发明人： Belleau, Bernard (deceased) ,  Belleau, Pierette ,  Nguyen-Ba, Nghe

IPC分类号： C07D473/00 ,  C07D411/04 ,  C07D411/14 ,  C07D327/04 ,  A61K31/52 ,  A61K31/505

CPC分类号： C07D411/14 ,  C07D327/04 ,  C07D405/04 ,  C07D411/04 ,  C07D473/00 ,  C07D473/40

公开(公告)号：EP0382526A3

公开(公告)日：1992-01-02

申请号：EP90301335.7

申请日：1990-02-08

申请人： BIOCHEM PHARMA INC.

发明人： Belleau, Bernard (deceased) ,  Belleau, Pierette ,  Nguyen-Ba, Nghe

IPC分类号： C07D473/00 ,  C07D411/04 ,  C07D411/14 ,  C07D327/04 ,  A61K31/52 ,  A61K31/505

CPC分类号： C07D411/14 ,  C07D327/04 ,  C07D405/04 ,  C07D411/04 ,  C07D473/00 ,  C07D473/40

摘要： Disclosed are compounds of the formula
wherein R₁ is hydrogen;
R₂ is a purine or pyrimidine base or an analogue or derivative thereof;
Z is S, S=O or SO₂; and
pharmaceutically acceptable derivatives thereof. Also described are use of the compounds as antiviral agents, pharmaceutical formulations, and methods for the preparation of the compounds.