公开(公告)号：EP2885277B1

公开(公告)日：2016-09-07

申请号：EP13739200.7

申请日：2013-07-17

申请人： Bayer CropScience AG

发明人： PAZENOK, Sergii ,  LUI, Norbert ,  TIMOSHENKO, Vadim Mikhailovich ,  KAMINSKAYA, Elena, Ivanovna ,  SHERMOLOVICH, Yuriy Grigorievich

IPC分类号： C07D231/16

CPC分类号： C07D231/16

公开(公告)号：EP2885277A1

公开(公告)日：2015-06-24

申请号：EP13739200.7

申请日：2013-07-17

申请人： Bayer CropScience AG

发明人： PAZENOK, Sergii ,  LUI, Norbert ,  TIMOSHENKO, Vadim Mikhailovich ,  KAMINSKAYA, Elena, Ivanovna ,  SHERMOLOVICH, Yuriy Grigorievich

IPC分类号： C07D231/16

CPC分类号： C07D231/16

摘要： A new process for the preparation of 5-fluoro-1
H -pyrazoles of the general formula (I), is described, resulting from the reaction of an olefin of the general formula (II) with hydrazines of the formula (III) R
1 -NH-NH
2 (III), wherein R
1 is selected from C
1 -C
6 alkyl, C
5 -C
10 aryl; R
2 is a trihalomethyl moiety with at least one fluorine atom; and R
3 is selected from C
1 -C
5 haloalkyl, CF
3 , C
2 F
5 , C
3 F
7 , CF
2 CF
2 CI, CFCICF
3 , in the presence of water and a base.