公开(公告)号：EP2595991B1

公开(公告)日：2017-04-26

申请号：EP11809371.5

申请日：2011-07-19

申请人： Ben Gurion University of The Negev Research And Development Authority ,  MOR RESEARCH APPLICATIONS LTD.

发明人： GOLAN, Avi ,  GOPAS, Jacob ,  OZER, Janet ,  EISNER, Nadav ,  BACHER, Adelbert ,  EISENREICH, Wolfgang ,  OSTROZHENKOVA, Elena ,  WINER, Hila

IPC分类号： A61K36/62 ,  A61K31/4747 ,  A61P29/00 ,  A61P31/12 ,  A61P35/00

CPC分类号： A61K31/438 ,  A61K31/4747 ,  A61K31/7048 ,  A61K33/24 ,  A61K36/62 ,  A61K2300/00

摘要： The current invention provides therapeutic methods which include inhibition of nuclear factor &kgr;b pathway in a cell based on the discovery of an active fraction of a plant extract termed NUP or a composition which includes NUP. NUP is used in treating and managing different diseases such as cancer, inflammation, and virus infections.

摘要翻译： 本发明提供了治疗方法，其包括基于发现称为NUP的植物提取物的活性部分或包含NUP的组合物来抑制细胞中的核因子κB途径。 NUP用于治疗和管理诸如癌症，炎症和病毒感染等不同疾病。

公开(公告)号：EP2595991A2

公开(公告)日：2013-05-29

申请号：EP11809371.5

申请日：2011-07-19

申请人： Ben Gurion University of The Negev Research And Development Authority ,  MOR RESEARCH APPLICATIONS LTD.

发明人： GOLAN, Avi ,  GOPAS, Jacob ,  OZER, Janet ,  EISNER, Nadav ,  BACHER, Adelbert ,  EISENREICH, Wolfgang ,  OSTROZHENKOVA, Elena ,  WINER, Hila

IPC分类号： C07D495/00 ,  C07D495/22

CPC分类号： A61K31/438 ,  A61K31/4747 ,  A61K31/7048 ,  A61K33/24 ,  A61K36/62 ,  A61K2300/00

摘要： The current invention provides therapeutic methods which include inhibition of nuclear factor κb pathway in a cell based on the discovery of an active fraction of a plant extract termed NUP or a composition which includes NUP. NUP is used in treating and managing different diseases such as cancer, inflammation, and virus infections.