公开(公告)号：EP4119557A1

公开(公告)日：2023-01-18

申请号：EP21767461.3

申请日：2021-03-10

申请人： CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

发明人： YANG, Anqi ,  ZHANG, Xiquan ,  WANG, Xunqiang ,  YU, Ding ,  GUO, Fangfang

IPC分类号： C07D471/04 ,  A61K31/519 ,  A61P35/00

摘要： The present invention belongs to the field of medicinal chemistry, and relates to a pharmaceutical combination comprising a pyridino[1,2-a]pyrimidinone compound. In particular, the pharmaceutical combination comprises a compound of formula I or a pharmaceutically acceptable salt thereof and a fulvestrant or a pharmaceutically acceptable salt thereof. The present invention also relates to the independent use of the pharmaceutical combination, or the compound of formula I or a pharmaceutically acceptable salt thereof in the treatment of breast cancer patients.