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公开(公告)号:EP1692100A1
公开(公告)日:2006-08-23
申请号:EP04808357.0
申请日:2004-12-09
申请人: CJ Corporation
发明人: CHO, Seong-Hwan, 721-602 Hyundai Apt. , LIM, Dong-Kwon, 109-1301 Samsung Raemian 1cha Apt , LEE, Kwang-Hyeg, B-1103 Doosan We've Jennis Apt. , YOUN, Yong-Sik, 105-1004 Byuksan Apt. , PARK, Choong-Sil
IPC分类号: C07C303/40 , C07C311/37
CPC分类号: C07C303/40 , C07B2200/07 , C07C311/46
摘要: Provided is a method of preparing an optically pure compound having formula 1 or its salts. The method includes: reacting ®-2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methylethylamine or its salts with a compound selected form the group consisting of chloroacetic acid, bromoacetic acid, fluoroacetic acid, iodoacetic acid, α-halogenoacetic acid anhydride, and α-halogenoacetyl halide in the presence of a base or an acylating agent.