公开(公告)号：EP3256168A1

公开(公告)日：2017-12-20

申请号：EP16749801.3

申请日：2016-02-10

申请人： Carnegie Mellon University

发明人： RUSSELL, Alan J. ,  MURATA, Hironobu

IPC分类号： A61K47/58

CPC分类号： C12N11/08 ,  C08L33/10 ,  C08L33/26 ,  C12N9/00 ,  C12N9/18 ,  C12N9/50

摘要： An enzyme-polymer conjugate shows increased activity and molecular dissolution in non-aqueous solvents enabling enzyme mediated catalysis in non-aqueous solutions. The inventions described in this specification relate to enzyme-polymer conjugates, organic solutions comprising enzyme-polymer conjugates, methods of dissolving enzyme-polymer conjugates in organic solvents, and methods of using enzyme-polymer conjugates, for example, in catalysis applications. The inventions described in this specification address the problems of insolubility and decreased activity of enzymes in non-aqueous solutions comprising, for example, organic solvents or ionic liquids.