公开(公告)号：EP1456163A2

公开(公告)日：2004-09-15

申请号：EP02788121.8

申请日：2002-12-16

申请人： Charterhouse Therapeutics Limited

发明人： ROBERTS, Stanley M.,University Liverpool ,  HAPPE, Alan M.,University Liverpool ,  SANTORO, Maria G.,University Rome,Dep. Biology ,  DAUVERGNE, Jerome,University Liverpool

IPC分类号： C07C49/753 ,  C07C323/22 ,  A61K31/122 ,  A61P25/28

CPC分类号： C07F7/1856 ,  C07C49/647 ,  C07C49/753 ,  C07C323/22 ,  C07C2601/08 ,  C07C2601/10

摘要： Compounds of formulae (I) or (II): wherein R is a substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl aralkenyl, or aralkynyl group, that optionally includes at least one heteroatom in its carbon skeleton, and R1 and R2 are H, or an -OR3 group in which R3 is a substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl aralkenyl, or aralkynyl group containing 4-12 carbon atoms, that optionally includes at least one heteroatom in its carbon skeleton, and R1 and R2 cannot both be H, and their use in therapeutic methods.

摘要翻译： 式（I）或（II）的化合物：其中R是取代或未取代的烷基，烯基，炔基，芳基，芳烷基芳烯基或芳炔基，其任选地在其碳骨架中包含至少一个杂原子， img id =“custom-character-00001”he =“2.12mm”wi =“1.02mm”file =“US20050124696A1-20050609-P00900.TIF”alt =“custom character”img-content =“character”img-format = “tif”/>和R？2 是H或-OR？3 组其中R 3 是取代或未取代的烷基，烯基 ，炔基，芳基， 芳烷基芳烯基或含有4-12个碳原子的芳炔基，其任选地在其碳骨架中包含至少一个杂原子，R 1 和R 2 不能都是H， 及其在治疗方法中的应用。