公开(公告)号：EP3978002A1

公开(公告)日：2022-04-06

申请号：EP21205348.2

申请日：2013-05-29

申请人： Chiesi Farmaceutici S.p.A.

发明人： ARCULUS-MEANWELL Clive Arthur ,  SKERJANEC, Simona ,  PRATS, Jayne ,  SCHNEIDER, David J.

IPC分类号： A61K31/7064 ,  A61P9/00

摘要： Methods of treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing percutaneous coronary intervention (PCI), comprising administering to the patient a pharmaceutical composition comprising cangrelor. The method may further comprise administering an additional therapeutic agent to the patient, the additional therapeutic agent comprising a P2Y 12 inhibitor. Pharmaceutical compositions useful for treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing PCI. The pharmaceutical compositions comprise cangrelor. Methods of preparing a pharmaceutical composition for treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing PCI, comprising admixing cangrelor with one or more pharmaceutically acceptable excipients. An ischemic event may include stent thrombosis, myocardial infarction, ischemia-driven revascularization, and mortality.