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    Artificial valve prosthesis with improved flow dynamics
    4.
    发明公开
    Artificial valve prosthesis with improved flow dynamics 审中-公开
    KünstlicheKlappenprothese mit verbesserter Flussdynamik

    公开(公告)号：EP2926772A1

    公开(公告)日：2015-10-07

    申请号：EP14183091.9

    申请日：2004-04-21

    申请人： Cook Medical Technologies LLC

    发明人： Case, Brian C. ,  Flagle, Jacob A. ,  Garrison, Michael L. ,  Hoffa, Andrew K. ,  Schaeffer, Darin G.

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2475 ,  A61F2002/068 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0037 ,  A61F2250/0039

    摘要： An expandable venous valve having a support structure (11) that configured to enlarge the area adjacent to the valve structure (12) such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus (34) adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.

    摘要翻译： 一种具有支撑结构（11）的可膨胀静脉瓣，所述支撑结构（11）构造成扩大邻近所述瓣膜结构（12）的区域，使得逆行流的流动模式被改变为有利于在 阀门区域，以防止静脉系统中的体液停滞，可导致血栓形成。 可以通过在两个支撑框架部分之间的血管壁的无支撑部分中形成邻近阀结构的人造窦（34）来产生扩大的口袋区域，或者支撑框架可以包括形成人造窦的扩张直径的中间或近端部分 邻近阀门结构。 在另一组实施例中，相对的小叶和支撑框架和/或血管壁之间的附接通路包括近端部分，其将小叶彼此延伸接触，并且远端部分相对于相邻壁形成大角度， 在传单的底部创造了一个大口袋。 在一个实施例中，附接通道沿着一对基本上平行的纵向连接支柱向远侧延伸以产生延伸的小叶接触区域，然后沿着远侧连接支柱周向地和远端地从前者角度定位以限定传单的底部边缘。

    Implantable vascular device
    6.
    发明公开
    Implantable vascular device 审中-公开
    ImplantierbarevaskuläreVorrichtung

    公开(公告)号：EP2601910A1

    公开(公告)日：2013-06-12

    申请号：EP13153763.1

    申请日：2003-08-15

    申请人： Cook Medical Technologies LLC ,  Oregon Health and Science University

    发明人： Pavcnik, Dusan ,  Case, Brian C. ,  Flagle, Jacob A ,  Garrison, Mike ,  Hoffa, Andrew K. ,  Leonard, Raymond B., II ,  Osborne, Thomas A. ,  Paul, Ram H., Jr. ,  Schaeffer, Darin G. ,  Sisken, Richard B.

    IPC分类号： A61F2/24 ,  A61F2/06 ,  A61F2/848

    CPC分类号： C25F3/24 ,  A61F2/2418 ,  A61F2/2439 ,  A61F2/2475 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/001 ,  A61F2230/0023 ,  A61F2230/0026 ,  A61F2230/0054 ,  A61F2230/0058 ,  A61F2230/0091 ,  A61F2230/0095

    摘要： A valve prosthesis (43), such as an artificial venous valve, having a support frame (11) and leaf structure comprising one or more leaflets (78, 79) in which the outer edge (112) of each leaflet engages the inner circumference of the bodily passageway along a serpentine path urged against the passageway by an expandable frame, while the inner edges move in response to fluid to restrict retrograde flow. Optionally, one or more elements (31, 32) can extend from the support frame/leaf structure to provide centering support and/or protection from the leaflet adhering to the vessel wall. In one embodiment, the centering support structure (164) comprises a second or third expandable frames (31, 32) attached to and extending from the proximal and/or distal ends of main valve structure and support frame. In another embodiment, one or more support elements extend outward from the valve support frame to engage the vessel wall to provide greater longitudinal stability.

    摘要翻译： 具有支撑框架（11）和叶结构的瓣膜假体（43），例如人造静脉瓣，叶片结构包括一个或多个单张（78,79），其中每个小叶的外边缘（112） 沿着蛇形路径的身体通道被可扩张的框架推向通道，而内边缘响应于流体而移动以限制逆行流动。 可选地，一个或多个元件（31,32）可以从支撑框架/叶片结构延伸，以提供定位支撑和/或防止附着在血管壁上的小叶。 在一个实施例中，定心支撑结构（164）包括附接到主阀结构和支撑框架的近端和/或远端的第二或第三可膨胀框架（31,32）。 在另一个实施例中，一个或多个支撑元件从阀支撑框架向外延伸以与容器壁接合以提供更大的纵向稳定性。