公开(公告)号：EP1329222A1

公开(公告)日：2003-07-23

申请号：EP02258707.5

申请日：2002-12-18

申请人： Daicho Kikaku Incorporated Company

发明人： Okada, Kenkichi ,  Ochiai, Akio ,  Kosuge, Masaki ,  Daicho, Takao ,  Tsuji, Kuniro ,  Nukaya, Haruo ,  Miura, Oto

IPC分类号： A61K35/78 ,  A61K35/60 ,  A61K35/413 ,  A61P39/00

CPC分类号： A61K45/06 ,  A61K31/366 ,  A61K35/413 ,  A61K35/60 ,  A61K36/23 ,  A61K36/258 ,  A61K36/284 ,  A61K36/31 ,  A61K36/344 ,  A61K36/36 ,  A61K36/481 ,  A61K36/484 ,  A61K36/725 ,  A61K36/734 ,  A61K36/8945 ,  A61K36/8969 ,  A61K36/899 ,  A61K2300/00

摘要： An object of the present invention is to provide a pharmaceutical agent or composition useful as a muscle-strengthening drug, an anti-inflammatory drug, an antiasthmatic, an antidiarrheal, an antidepressant, or a drug for the treatment of secondary diseases following cerebral infarction, motor paralysis, diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional cardiopathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, and a dermatological agent or composition suitable for skin applications, which can treat or prevent muscle weakening and inflammation, in particular arthritis, by its muscle-strengthening and/or anti-inflammatory actions, said agent or composition comprising isoflavone and/or isoflavone glycoside in combination with a pungent substance, a bitter substance or a sour substance, and cholic acid, and/or scymnol and/or a scymnol ester. The present invention relates to an agent or composition usuful as a muscle-strengthening drug, an anti-inflammatory drug, an antiasthmatic, an antidiarrheal, an antidepressant, or a drug for the treatment of secondary diseases following cerebral infarction, motor paralysis, diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional cardiopathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, and/or an agent or composition to be applied to the skin, said agent or composition comprising isoflavone and/or isoflavone glycoside in combination with a pungent substance, a bitter substance or a sour substance, and cholic acid, and/or scymnol and/or a scymnol ester.

摘要翻译： 本发明的目的在于提供可用作治疗脑梗塞后继发疾病的肌肉强化药物，抗炎药物，抗哮喘药物，止泻药物，抗抑郁药物或药物的药物或组合物， 运动性麻痹，视力减退，肝炎，炎性肠综合征，功能性肠病，功能性心脏病，功能性肝病，功能性肾病，痴呆，更年期症状，老年性痴呆和/或阿尔茨海默病，以及适用于皮肤应用的皮肤病药剂或组合物， 可以通过其肌肉强化和/或抗炎作用来治疗或预防肌肉弱化和炎症，特别是关节炎，所述药物或组合物包含异黄酮和/或异黄酮糖苷与辛辣物质，苦味物质或酸味 物质和胆酸，和/或樟脑和/或樟脑油酯。 本发明涉及用于治疗脑梗塞后的继发性疾病，运动​​性麻痹，减少或减轻以下疾病的肌肉强化药物，抗炎药物，抗哮喘药物，止泻药物，抗抑郁药物或药物的药剂或组合物 视力，肝炎，炎性肠综合征，功能性肠病，功能性心脏病，功能性肝病，功能性肾病，痴呆，更年期症状，老年性痴呆和/或阿尔茨海默病，和/或待施用于皮肤的药剂或组合物， 包含异黄酮和/或异黄酮糖苷与刺激性物质，苦味物质或酸性物质以及胆酸，和/或樟脑酚和/或樟脑酚酯组合的组合物。