专利检索 ap:("EGIS GYÓGYSZERGYÁR RT.") AND inv:"BARKOCZY, Jozsef" 第 1 页

1.

发明授权
8-CHLORO-2,3-BENZODIAZEPINE DERIVATIVES 有权
标题翻译： 8-氯-2,3-二BENZODIAZEPINDERIVATE

公开(公告)号：EP1660462B1

公开(公告)日：2008-11-19

申请号：EP04769081.3

申请日：2004-07-29

申请人： EGIS GYÓGYSZERGYÁR RT.

发明人： BARKOCZY, Jozsef , LING, István , SIMIG, Gyula , SZÉNÁSI, Gábor , GIGLER, Gábor , KERTÉSZ, Szabolcs , SZÜCS, Gyula , SZABÓ, Géza , VÉGH, Miklós , HÁRSING, László, Gábor

IPC分类号： C07D243/02

CPC分类号： C07D243/02

摘要： The invention relates to new 8-chloro-2,3-benzodiazepine derivatives of the general formula (I),wherein R stands for a lower alkyl group or a group of the general formula -NH-R', wherein R' stands for a lower alkyl or a lower cycloalkyl group), and pharmaceutically acceptable acid addition salts thereof. The invention also encompasses a process for the preparation of said compounds, pharmaceutical compositions containing them and new intermediates useful for the preparation of the new 8-chloro-2,3-benzodiazepine derivatives.The compounds according to the invention possess AMPA/kainate receptor inhibiting activity.