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    Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
    1.
    发明公开
    Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate 失效
    Loracarbef Isopropanolat und Umwandlungsverfahren vom Isopropanolat in Loracarbef Monohydrat。

    公开(公告)号：EP0627429A1

    公开(公告)日：1994-12-07

    申请号：EP94303942.0

    申请日：1994-06-01

    申请人： ELI LILLY AND COMPANY

    发明人： Henning, William Carl ,  O'Dea, Michael Eugene

    IPC分类号： C07D463/00

    CPC分类号： C07D471/04 ,  C07D463/22

    摘要： The invention is directed to the crystalline isopropyl alcohol solvate of loracarbef, and also is directed to a process for the preparation of the crystalline monohydrate form of the compound of formula (I)

    which includes exposing the crystalline isopropyl solvate form of the compound of formula (I) to a temperature of between about 50° and 90°C and a relative humidity of between about 60 to about 100%.

    摘要翻译： 本发明涉及劳拉卡贝的结晶异丙醇溶剂化物，还涉及制备式（I）化合物的结晶一水合物形式的方法，其包括将化合物的结晶异丙基溶剂合物形式 （I）的温度至约50-90℃的温度和约60至约100％之间的相对湿度。