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公开(公告)号：EP1390063B1
公开(公告)日：2004-11-17
申请号：EP02748680.2
申请日：2002-04-29
CPC分类号： A61K31/472 , A61K9/146 , A61K9/2031
摘要： A solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate is provided comprising amorphous nelfinavir mesylate, and a pharmaceutically acceptable, water soluble, non-ionic synthetic block copolymer of ethylene oxide and propylene oxide, said copolymer having a melting point of at least 40°C. A hot melt granulation process for making the dosage form is provided.
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公开(公告)号：EP1390063A2
公开(公告)日：2004-02-25
申请号：EP02748680.2
申请日：2002-04-29
CPC分类号： A61K31/472 , A61K9/146 , A61K9/2031
摘要： A solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate is provided comprising amorphous nelfinavir mesylate, and a pharmaceutically acceptable, water soluble, non-ionic synthetic block copolymer of ethylene oxide and propylene oxide, said copolymer having a melting point of at least 40°C. A hot melt granulation process for making the dosage form is provided.
摘要翻译： 提供了无定形奈非那韦甲磺酸盐的固体单位口服药物剂型，其包含无定形奈非那韦甲磺酸盐和环氧乙烷和环氧丙烷的药学上可接受的水溶性非离子合成嵌段共聚物，所述共聚物的熔点为至少40° C。 提供了制备该剂型的热熔造粒方法。
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公开(公告)号：EP1646369B1
公开(公告)日：2019-04-10
申请号：EP04763093.4
申请日：2004-07-05
发明人： ALBANO, Antonio, A. , INFELD, Martin, Howard , PHUAPRADIT, Wantanee , SHAH, Navnit-Hargovindas , ZHANG, Lin
IPC分类号： A61K9/16 , A61K9/20 , A61K31/551 , A61P31/18
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