专利检索 ap:("GENZYME CORPORATION" OR "THE REGENTS OF THE UNIVERSITY OF MICHIGAN") AND inv:"COPELAND, Diane" 第 1 页

1.

发明公开
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INHIBITORS 有权
标题翻译： N-乙酰基鞘氨醇葡糖基转移酶抑制剂

公开(公告)号：EP1409467A1

公开(公告)日：2004-04-21

申请号：EP02750099.0

申请日：2002-07-16

申请人： GENZYME CORPORATION , THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： HIRTH, Bradford, H. , SIEGEL, Craig , SHAYMAN, James A. , NELSON, Carol Anne , HARRIS, David J. , COPELAND, Diane

IPC分类号： C07D295/12 , C07C231/18 , C07C215/30 , C07C237/20 , C07D498/04

CPC分类号： C07D405/06 , A61K31/4025 , C07D295/185 , C07D319/18 , C07D498/04

摘要： Disclosed is a novel enantiomeric synthesis of ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.

2.

发明授权
A N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INHIBITOR 有权
标题翻译： N-乙酰基鞘氨醇葡糖基转移酶抑制剂

公开(公告)号：EP1409467B1

公开(公告)日：2012-04-18

申请号：EP02750099.0

申请日：2002-07-16

申请人： GENZYME CORPORATION , THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： HIRTH, Bradford, H. , SIEGEL, Craig , SHAYMAN, James A. , NELSON, Carol Anne , HARRIS, David J. , COPELAND, Diane

IPC分类号： C07D319/18

CPC分类号： C07D405/06 , A61K31/4025 , C07D295/185 , C07D319/18 , C07D498/04

摘要： Disclosed is a novel enantiomeric synthesis of ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.